Bacillus coagulans, also known as Lactobacillus sporogenes, is a gram-positive, spore-forming probiotic which is characterized by the increased survival in acidic gastric environment and in bile-acid-associated duodenal environment as compared to the commonly used probiotic microorganisms. Bacillus coagulans does not adhere to the human intestinal epithelium and is completely eliminated in four to five days unless chronic administration is maintained.
Once in the intestines, Bacillus coagulans is activated and releases anti-inflammatory molecules or acts indirectly to eradicate organisms in the gut responsible for the inflammatory immune response. Activated Bacillus coagulans produces bacteriocins and lowers local pH by producing L(+) lactic acid that, along with competition for sites of mucosal adherence, works to dislodge and eliminate any antagonizing microbes that may be contributing to an inflammatory response. Bacillus coagulans also produces short-chain fatty acids such as butyric acid, a compound known to support the health and healing of cells in the small and large intestines and to contribute to modulation of the mucosal immune system.
Potential indications for use of Bacillus Coagulans in humans include:
- Irritable bowel syndrome
- Inflammatory arthritis/rheumatoid arthritis
- Adjunct therapy for lactose and fructose intolerance
- Clostridium difficile-associated colitis
- Antibiotic-associated diarrhea
- Immunostimulatory activity
- Prophylaxis of upper respiratory viral infections
- Anti-fungal/anti-yeast therapy
- Treatment of yeast and bacterial vaginal infections
Potential side effects:
- Infrequent bloating
Potential drug interactions:
- Have not been reported
- Severe immunosuppression
Complementary natural products:
- Mannan Oligosaccharides
- Saccharomyces Boulardii
Contents: 100 caps
The recommended dose of Bacillus coagulans varies from 25 to 75 billion Colony Forming Unit (CFU) a day. Take on an empty stomach 20 to 30 minutes before meal.
Bacillus coagulans is an extremely stable probiotic and does not need to be refrigerated.
Contains no: wheat, gluten, soy, milk, shellfish or preservatives.
Baron M. A patented strain of Bacillus coagulans increased immune response to viral challenge. Postgrad Med. 2009 Mar;121(2):114-8.
Czaczyk K, Trojanowska K, Mueller A. Antifungal activity of Bacillus coagulans against Fusarium sp. Acta Microbiol Pol. 2002;51(3):275-83.
Dolin BJ. Effects of a proprietary Bacillus coagulans preparation on symptoms of diarrhea-predominant irritable bowel syndrome. Methods Find Exp Clin Pharmacol. 2009 Dec;31(10):655-9.
Hun L. Bacillus coagulans significantly improved abdominal pain and bloating in patients with IBS. Postgrad Med. 2009 Mar;121(2):119-24.
Mandel DR, Eichas K, Holmes J. Bacillus coagulans: a viable adjunct therapy for relieving symptoms of rheumatoid arthritis according to a randomized, controlled trial. BMC Complement Altern Med. 2010 Jan 12;10:1.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
All information contained on this website is intended for informational and educational purposes only, and is not intended nor suited to be a replacement or substitute for professional medical treatment or for professional medical advice relative to a specific medical question or condition.
- Abnormal Intestinal Microflora
- Antibiotic-Associated Diarrhea
- Inflammatory Bowel Disease/Ulcerative Colitis
- Intestinal Yeast/Candida
- Irritable Bowel Syndrome
- Lactose Intolerance
- Prevention of Chemotherapy Complications
- Rheumatoid Arthritis
- Upper Respiratory Infections/Sinusitis