Artemisinin is traditionally used as an anti-malarial. Dr. Shikhman discuss the many other successfu
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So today we'll talk about another important part of
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the family of Gluten Free Remedies, which is Artemisinin.
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Artemisinin, also known in traditional Chinese
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medicine as qinghao su. It's biologically active
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ingredient, or constituent, which is found in Artemisia
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annua which is sweet wormwood. Again, this is a traditional
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Chinese remedy. So Artemisinin is a chemically
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defined remedy which was discovered by a Chinese
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scientist, Tu Youyou, and because of this discovery
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she got the Nobel Prize last year. So traditionally,
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Artemisinin as well wormwood have been used as
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anti-malarial remedies.
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So however over the last ten years, its been discovered
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that Artemisinin possesses broad biological activity.
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Not only does it work against malaria, it also works
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against various parasites. It works against certain
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worms, intestinal worms specifically. It has a very broad
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anti-microbial activity. And what is interesting is that
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it has very strong activity against Helicobacter pylori, or h. pylori
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a main microorganism causing ulcers and gastric cancer.
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It can be used as a combination therapy and is very
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efficient as a part of a combination therapy.
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In addition, Artemisin also possesses very strong
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anti-viral activity. Specifically against broad spectrum
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of herpes viruses. And these viruses in addition
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to HSV 1, 2, and 6 also include Epstein barr virus,
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and cytomegalovirus. We've been using this product
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in our clinic specifically to inhibit these infections,
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and our results are quite impressive.
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So the newest discovery about Artemisinin is that
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it also destroys microbial biofilms. And there are several
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publications saying it can be used to treat resistant
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yeast infections in combination with anti-fungal therapies.
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So in addition to its anti-viral, anti-microbial, and
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anti-parasitic activity, Artemisinin is know as an
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anti-cancer agent. It used as a solo agent and in
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combination with various chemotherapeutic agents
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to treat various forms of cancer. Such as leukemia,
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prostate cancer, liver cancer, stomach cancer, and
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lung cancer. Artemisinin also has very strong
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anti-inflammatory activity and there are several
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mechanisms of actions which it expresses. One of them
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is an inhibition of B-lymphocyte activity and proliferation.
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And because of that, there are more and more data
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that Artemisinin can be used to treat various
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autoimmune diseases such as lupus, rheumatoid
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arthritis and Sjogren's syndrome as a solo agent
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and as a part of combination therapy.
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Over the last several years we've been using
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Artemisinin in our practice to treat lupus, early
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rhuematoid arthritis and Sjogren's syndrome.
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And again, I am very impressed with our early outcomes.
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So Artemisinin can be used as solo therapy as a single
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herb, but it can also be used very efficiently in
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combination with other herbs. For example, in patients
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who have lupus and Sjogren's syndrome, we use
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Artemisinin in combination with Cordyceps Sinensis,
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which is a Chinese mushroom. To treat various
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infections inclusing for example, H. pylori, we can use
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Artemisinin in combination with Olive Leaf Extract
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Sometimes patients don't tolerate well the so-called
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die-off effect, or Herxheimer Reaction, and we are
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combining Artemisinin with Succinic Acid. Also for
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various infections, Artemisinin can be combined with
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Anantamul, Cat's Claw and Black Walnut.
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Quite frequently, we get questions whether drugs
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and herbs can be combined and what's the outcome
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of that combination? Specifically in patients with
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autoimmune diseases, we frequently combine
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Artemisinin with Plaquenil, also known as
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Hydroxychloroquine. It can be used in combination
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with quinacrine, low dose naltrexone and some other
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agents from the arsenal of Western medicine.
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For example, the recent discovery is that Artemisinin
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amplifies the anti-fungal activity of miconazole
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which is a known agent prescribed frequently to
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treat candida.
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In addition in our practice we also combine
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Artemisinin with certain anti-viral agents to treat
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Eptsein barr virus and cytomegalovirus infections.
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And again that combination is very well tolerated
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with very few if any side effects.
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Although Artemisinin in general is very well tolerated,
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you need to know that it is a very powerful
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and very strong remedy. In our clinic we observed
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several patients who demonstrated elevation of
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liver function. And therefore, we introduced the rule
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that patients who are getting Artemisinin need to
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be tested for their liver function every 1 or every 3
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months depending on the duration of the therapy.
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My personal advice is to take Artemisinin under
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physician supervision. In addition it is absolutely
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obligatory not to take Artemisinin in combination with
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alcohol because your chances of having elevated liver
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function goes up dramatically.
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And also based on published data, Artemisinin is
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strongly contraindicated for women who are
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pregnant especially during the first trimester of pregnancy.
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So today we'll talk about the new addition
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to the family of Gluten Free Remedies.
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The new product is Sulbutiamine Plus.
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This is the first brain permeable Vitamin B1
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which is designed to treat mainly patients with
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chronic fatigue. The story behind Sulbutiamine
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is quite interesting. So what's been shown
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many years ago that patients who have
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chronic fatigue syndrome, they have low levels
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of Vitamin B1 in their brain tissue not in the blood
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or peripheral tissues. And what is more interesting
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is that if you take Vitamin B1 in the native form,
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it doesn't penetrate into the brain tissue well enough.
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And people with chronic fatigue syndrome are
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still deficient of this vital vitamin.
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So the first attempt was to create a first generation
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of Vitamin B1 with better fat solubility and better penetration
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into the brain and so the first vitamin was Benfotiamine,
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but still it barely penetrated into the brain through
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the blood-brain barrier. So a few years ago in Japan
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a new product was designed, which is Sulbutiamine.
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Sulbutiamine represents a dimer of Vitamin B1
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or thiamin. What it means is two molecules of
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Vitamin B1 are bound together.
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So it's extremely lipophilic meaning that it's fat soluable
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and because of that, it penetrates into the brain tissue
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much much better than thiamin or Benfotiamine.
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So what's been shown in many clinical studies
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as well as in animal studies that Sulbutiamine can cross
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through blood-brain barrier and it converts into
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the real Vitamin B1, which is a biologically active B1
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within the brain tissue. So outside of the United States
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in Japan and in Europe, Sulbutiamine is used as a
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prescription remedy to treat chronic fatigue syndrome
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and weakness specifically due to chronic infections.
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For example, Lyme disease, chronic streptococcal infections,
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mycoplasma infection, Epstein-Barr virus, CMV and
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so on and so on. As well as a remedy to treat fatigue
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due to various inflammatory processes such as
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multiple sclerosis for example.
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So we decided to improve the efficacy of just plain
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Sulbutiamine and so I found a lot of studies on its
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mechanism of action and permeability into the brain tissue.
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And we came up with a proprietary formulation
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which in addition to Sulbutiamine contains also
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Milk Thistle, Aplha Lipoic Acid, and Piperine.
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And this product is supposed to have better
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biological availability of Sulbutiamine.
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So what is known about the mechanism of
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Sulbutiamine activity? So the data came from
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mainly animal research as well as clinical studies.
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So what is shown is that Sulbutiamine protects
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neuronal cells from oxygen and glucose deprivation.
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It restores nerve function in patients with diabetic neuropathy.
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So it can be used as adjunct therapy for those who
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suffer from diabetes and who have nerve damage
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from diabetes. So it also improves neuronal cell
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communication within the brain. And that is something
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which is mediated via glutamine, choline, and
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dopamine-dependent pathways and corresponding
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receptors. So in clinical trials it has been shown
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that Sulbutiamine definitely improves memory and it
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can be used in patients with brain fog and some
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minor cognitive problems. It reduces fatigue and
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also what is more important is that it slows down
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or attenuates neuronal cell death and therefore it can be
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used in patients who sustained strokes within
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a day or so after the acute onset of the stroke.
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So based on the mechanism of its activity,
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Sulbutiamine Plus should be very synergistic with
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DMAE Plus, and that's something which we are using
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in our clinic. The combination of DMAE Plus, plus
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Sulbutiamine Plus. It also should be very synergistic
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with major methylators such as methyl B12 or
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methylcobalamin as well as methylfolate. In addition
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there is a mechanism which links Sulbutiamine to
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7-Keto and Pregnenolone. Also Sulbutiamine can
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amplify the efficacy of Cordyceps, Rhodiola, and Eleutherococcus.
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So in general based on our personal clinical
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observations this is a product which is very well
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tolerated without any major side effects. There is
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one warning. Certain clinical publications indicate
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that Sulbutiamine Plus cannot be used in patients
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with poorly controlled bipolar disorder.
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Because it can worsen specifically manic episodes.
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And therefore we don't recommend to use this
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particular supplement for patients who deal with
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that disorder.
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Today we will talk about prevention of the skin aging
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and treatment of the aged skin in a natural way.
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Some patients ask me why
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you stepped into a territory which is not
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pure rheumatology or pure autoimmune diseases
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but, it happened kind of organically.
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In our practice we have a lot of patients with gluten intolerance
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and various autoimmune diseases
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and these are the patients who are prone to
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premature aging of the skin
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and I was trying to find a natural solution to the problem
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and that's how we started our journey
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So how do we know that
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the skin ages? Well first of all you can
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wrinkles, you can see sagging of the skin.
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Changes in the skins results
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in reduced skin strength and elasticity.
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In addition the skin gets thinner, the subcutaneous fat disappears
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and the skin gets very, very prone to
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various erosions and tear and bleedings
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as well as subcutaneous bruises.
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In addition, the aged skin cannot repair itself
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fast enough and wounds typically heals much, much
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longer as compared to young patients.
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So this aging process can also contribute to
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skin ulcers and various skin infections.
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So we decided to simplify the approach to
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treat the aged skin and we developed several principles.
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Number one, we need to restore skin elasticity.
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So how can we do it?
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We need to increase production of collagen in
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the skin and we came up with two products
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which do it extremely well.
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The first product is TruMarine Collagen
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it's a Japanese product which represents
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very high-end collagen from fish skin.
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And second is vitamin C plus rosehips
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these are natural remedies
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which facilitate collagen production.
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Second you want to improve skin hydration
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and again, how can we do it?
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TruMarine collagen is a wonderful product
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to improve skin hydration
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and we decided to add hyaluronic acid
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which is a natural skin matrix
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and it retains water in the skin.
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So this is a win-win situation
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to improve skin hydration
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and skin moisture.
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The next step was trying to find a natural
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solution to improve skin repair
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and to improve the skins ability to
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heal up the ulcers and wounds
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and things like that.
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Again, TruMarine collagen makes wonders
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and finally two extra products
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which can be used very efficiently.
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It's biotin, which is a vitamin
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and Eclipta Alba, which is a famous
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Ayruvedic herb.
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In addition, biotin and eclipta alba
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stimulate nails and hair growth
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and so they can be used for this purpose.
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And finally we are talking about some cosmetic things.
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Obviously none of us wants to deal with wrinkles
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and poor tonus of the skin
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and there is a product which is an extract from
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sardines, it's called DMAE
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which stands for 2-dimethylaminoethanol
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and this is a product in clinical trials
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was shown to reduce wrinkles
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and improve skin tonus.
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So, what does it do?
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When you consume collagen,
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it degrades into amino acids
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and these amino acids migrate
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to your skin and they boost
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production of your own collagen. So that's why we
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talk about beauty from within, or beauty from the inside.
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So the newly synthesized collagen
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in your skin, increases skin elasticity
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it increases water absorption and retention
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in the skin and in addition
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one thing which we haven't mentioned
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it reduces the skin damage produced by
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ultraviolet light or sunlight.
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So the product has been on the European
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and Japanese market for several years
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and we are proud to be one of the first
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companies in the United States who introduce
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it to the U.S. customers.
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There are quite a few clinical trials
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which were published using TruMarine
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Collagen. And what's been shown that
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after taking it for three weeks
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and up to seven weeks, you can see visible
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changes in the skin. Including
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improvement of skin elasticity and skin tonus.
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The studies were done mainly in women
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but our position is that there is no
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gender differences and the product should
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work for both men and women.
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Another study done by the same company
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showed that TruMarine Collagen
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increases water retention and moisture content
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in the skin and subcutaneous tissue.
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It was a very nicely done study and
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results were obviously statistically significant
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Again, the typical duration of
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the study when you can see an
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obvious difference was two months.
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In addition, the company made a phenomenal
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observation, they actually did an animal
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study where they fed animals with
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TruMarine Collagen and then analyzed
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the skin microscopy and specifically collagen
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fibers. So what they observed is consumption
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of TruMarine Collagen by animals
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results in an increase of the collagen
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fiber diameter, which is the thickness,
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and density.
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This also stimulates production of fibroblasts.
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These are main cells which contributes
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to various skin properties.
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Again both in animal experiments and
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in humans, the product demonstrates
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phenomenal beneficial properties
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and definitely can be used very efficiently
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as a skin anti-aging product.
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The same company also ran the final
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study on TruMarine Collagen as a product
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preventing sunlight or UV induced
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skin damage and again, results were very
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very impressive, very beneficial.
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So today we will talk about integrative therapy
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for Sjogren's Syndrome. This is the protocol which
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was developed in our clinic which is Institute for Specialized Medicine
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together with Gluten Free Remedies.
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As most of you know Sjogren's Syndrome is the most common autoimmune disease affecting humans
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and specifically the disease affects women. It's much more prevalent among women than in men.
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Sjogren's Syndrome is known as a disease which can cause dryness
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and dryness can affect eyes, mouth as well as genital organs.
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So the dryness can be very debilitating and create problems with eye vision, extreme thirst and with different
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sexual dysfunctions. In addition, Sjogren's Syndrome can cause muscle pain, joint pain
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various gastrointestinal problems, neurological problems as well as problems with cognitive function.
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So Sjogren's Syndrome is an autoimmune disease which affects mainly exocrine glands. These
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are the glands which produce saliva and tears as well as glands producing various digestive enzymes, such as pancreas.
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And also it can affect glands producing sweat.
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The mechanism linked to Sjogren's Syndrome is definitely an autoimmune process
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and it results in infiltration of various exocrine glands with lymphocytes.
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Subsequently these lymphocytes become activated and they destroy normal gland tissue
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and the organ becomes dysfunctional.
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There are several key mechanisms which contribute to Sjogren's Syndrome.
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Right now there is a thinking process behind Sjogren's Syndrome that it is an autoimmune disease
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which obviously has a genetic background, but at the same time is strongly linked to certain viruses.
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Such as Epstein Barr virus known as EBV
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and cytomegalovirus known as CMV.
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So as a consequence of interplay between various viral infections and genetic factors the immune system
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gets out of control. And then what happens?
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Number one the process results in the changes in TH1 and TH2 ratio. These are T cells which mediate various
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aspects of our immune balance and the TH1 cells become dominant and they trigger various
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autoimmune responses. The second mechanism is linked to so called TH17 cells and disbalance
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between T cells which regulate normal immune response and autoimmune responses.
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As a consequence there is increased production, proliferation of TH17 cells.
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In addition, there are several well recognized markers of Sjogren's Syndrome
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which also facilitate various autoimmune problems.
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So first of all these include antibodies to SSA and SSB antigens. These antibodies are definitely pathogenic
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and they have been associated with various pathological processes.
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In addition, recently another subset of antibodies have been recognized as pathogenic.
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These are antibodies which affect muscarinic M3 receptor
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So after interaction between antibodies and M3 receptor there is a downstream event
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which affects water channel knows as aquaporin-5. And as a consequence, the cells start producing
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less and less fluid and our saliva for example gets much more viscous
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our tears become much more viscous. And so this is the whole mark of Sjogren's Syndrome.
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In addition over the last several years another pathogenic process was recognized
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and the process was linked to abnormal methylation of epithelial DNA in epithelial cells.
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As some of you know methylation is a process which regulates switching of the gene on and off
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and defective methylation can reactivate genes which in normal conditions should be dormant.
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Therefore abnormal methylation is another pathogenic process which contributes to reactivation of the autoimmune response.
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So based on pathogenisis and clinical symptoms of Sjogren's Syndrome
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there are three main goals in the therapy of Sjogren's Syndrome.
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And these goals can be achieved with either drugs or natural products and today we'll talk about natural approach to treat Sjogren's Syndrome
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and this approach can be as efficient as drugs.
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So the first process is a process focused on improving dryness
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Second we need to normalize poorly controlled autoimmune responses
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and finally one topic which also needs to be in focus is prevention of malignancies.
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So what's been shown is that patient's with Sjogren's Syndrome have significantly increased risk
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of malignancies specifically lymphomas. And controlling of Sjogren's Syndrome activity
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can significantly reduce the risk of lymphomas.
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So what is our recipe? So we created a protocol where we are using a combination of
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several natural products. And each of these products target one or two specific pathogenic mechanisms.
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So how can we improve dryness? We are using three natural products
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which we've found to be very efficient in our practice
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One is a product called SalivaStim and two oils one is Black Currant Seed Oil and Krill Oil.
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The next process is focused, or the next approach is focused on normalization of autoimmune responses.
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And for this reason we are using an extract from wormwood known as Artemisinin
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we are using a famous Chinese mushroom which is Cordyceps Sinensis
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we are using N-Acetylcysteine, we are using very concentrated broccoli extract containing high
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concentration of I3C/DIM, which is indole-3-carbinol and DIM
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as well as Krill Oil and Black Currant Seed Oil.
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Another therapeutic path is the correction of methylation defect
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that's something which can be achieved with a product called TMG Plus.
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TMG stands for Trimethylglycine, which is a key methylation agent. In addition TMG Plus
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contains methyl B-12, Methylfolate and B6.
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The normalization of methylation process is a key step in controlling of Sjogren's Syndrome.
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Finally one of the goals is to prevent malignancies or to reduce the risk of malignancies.
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And this can be achieved with three products such as
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Artemisinin, Indole-3-Carbinol/DIM and SalivaStim.
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Now we'll talk briefly about certain products that we have in our arsenal.
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The first one is Artemisinin. So Artemisinin is a chemically defined substance
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from the Chinese herb known as Wormwood. So Artemisinin has a unique scope of activities
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it does inhibit very efficiently Epstein Barr Virus and Cytomegalovirus and this unique property of
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Artemisinin we are using all of the time in our practice.
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Artemisinin also inhibits TH1 responses and it shifts TH1/TH2 ratio toward TH2.
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It also suppresses TH17 cells which facilitate autoimmune responses. And finally
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there is very strong data that Artemisinin can inhibit abnormal B cell proliferation and suppress
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autoantibody production. SalivaStim is another featured product of Gluten Free Remedies
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SalivaStim is unique because it increases expression of Aquaporin-5
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and in many clinical trials was shown to increase production of saliva and tears.
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And this is the product which it's strength is very very similar to a lot of prescription products such as
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Pilocarpine and Cevimeline known as Evoxac in terms of stimulation of saliva and tear production.
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N-Acetylcysteine is another natural product which can optimize TH1 and TH2 ratio
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as well as inhibit TH17 responses. In addition it is one of the strongest natural antioxidants
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and it stimulates production of glutathione. It is well recognized that the production of glutathione
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is inhibited in patient's with Sjogren's Syndrome.
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Another natural product which is a part of our scope of remedies for Sjogren's Syndrome is Indole-3-Carbinol/DIM
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As I mentioned before it is a natural highly concentrated extract from broccoli sprouts
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so I3C/DIM optimize TH1/TH2 responses.
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It protects salivary and lacrimal glands from the damaging effects of estrogens.
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It is very well recognized that women who are over producers of estrogen are at high risk of having Sjogren's Syndrome.
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In addition it protects epithelial cells and lacrimal glands from certain environmental factors
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and it also possesses a very strong antiviral activity.
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Black Currant Seed Oil and Krill Oil are natural products which normalize TH1 and TH2 responses
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as well as inhibit various inflammatory processes through COX1/COX2 mechanisms.
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Cordyceps Sinensis is used in our practice as a very very synergistic product with Artemisinin
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It's a classical combination of traditional Chinese medicine. In addition by itself it has certain
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antiviral and antimicrobial activity and it is also capable of normalizing TH1 and TH2 responses.
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The next slide shows the dosage regime which we are using in our practice.
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There are a couple of comments that I want to make
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In general, we start our patients on one product at a time
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and we try one product for three or four days, see
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how patients tolerate them and then we will move forward with the second one.
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So among all products that are listed on this slide, I
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want to specifically mention Artemisinin.
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As a part of good practice, I would strongly recommend
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to check liver function at least every 6-8 weeks
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in patients who take Artemisinin.
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Because there is a small chance that Artemisinin can cause non-specific liver damage
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and elevation of liver enzymes.
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So Sjogren's Syndrome not only affects salivary glands
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and lacrimal glands, but also can cause a number
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of satellite problems such as various gastrointestinal
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problems including dysmotility, poor production of
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digestive enzymes and so on and so on.
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And because of the dryness quite a few patients who have Sjogren's Syndrome
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they are dealing with chronic candida or yeast infection.
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Because of that we are using some supplements as a part of
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the adjunct therapy. These supplements include
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known things such as digestive enzymes
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Triphala, which helps us to move the bowel.
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Probiotics, prebiotics and the scope of leaky gut products which are available as a part of Gluten Free Remedies
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In addition, as a part of candida control or yeast control
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we are using our featured product Candidacillin
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in a combination with Berberine and Black Walnut Hulls.
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That's the protocol which we would like to introduce and that's the protocol which we have been using in
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our practice for a while with great success.
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Today we will talk about gout.
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Gout is one of the most common forms of arthritis,
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which we see in our clinic. And it affects males and females.
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It affects mainly women after menopause
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and in terms of men, it affects men independent from their age.
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We have actually young males with gout and old males with gout.
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So what is gout? Gout is a form of arthritis
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Which is caused by elevated levels of uric acid.
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When uric acid reaches critical concentrations
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it forms crystals and the crystals are deposited in various joints
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causing inflammation, pain and swelling of the affected joints.
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What do we need to know about uric acid?
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Uric acid is produced in the liver mainly
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the main enzyme which is responsible for production
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of urid acid is called xanthine oxidase. And most
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of the drugs available on the market right now
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are specifically targeting this enzyme.
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Elimination of uric acid is mediated mainly through
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kidneys, approximately 60-70% of uric acid
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produced in our body is eliminated through kidneys
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and the rest through the gastrointestinal tract.
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So we are talking about 30-40%.
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There is an enzyme which can also participate in
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degredation of uric acid and it has a long name
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Hypoxanthine-guanine Phosphoribosyltransferase
26
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and there is an abbreviation for that enzyme; it's called HGPRT
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This is a critical enzyme which is kind of opposite
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of xanthine oxidase and this enzyme lowers levels of uric acid.
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At this point there are not too many drugs available
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to control these enzymes, but there are quite a few supplements available.
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So what is interesting is that genetically in males,
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activity of this particular enzyme is much lower than in females
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and it's one of the reasons why young males have
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much more problem with gout than young women.
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When we are dealing with gout, there are two issues
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which we need to discuss. Issue number one, how
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do we deal with acute gouty attacks when a person or patient is in severe pain.
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And number two how do we control uric acid level
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from being elevated and how we can prevent the
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development of crystals, and how we can prevent
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flare ups of gout. We are not going to talk about
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medications because you can find plenty of
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information on the internet and in various publications.
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Today we will talk mainly about natural way of dealing with gout
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Actually, the number of natural supplements
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available for gout is much more than the number of drugs
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available for gout. So if a person or patient has an
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acute gouty attack what do we do?
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We are using herbs and supplements which have
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strong anti-inflammatory activity. For example, in
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our clinic we are using a very popular herb. It's called
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Devil's Claw, in addition we are using an herb from
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Amazonian rainforest from Peru, it's called Iporuru
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Also we are using Boswellia/Curcumin for the same reason
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and in addition, what's been shown is that
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high-dose fish oil combined with Methylfolate
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and Alpha Lipoic Acid can significantly reduce an acute
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inflammatory reaction caused, or triggerd by uric acid crystals.
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Next step is prevention of gouty attacks or maintenance of gout.
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So how do we handle it? So there are several
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natural remedies which are very efficient.
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Number one is White Chinese Mulberry Extract
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known as morus albus. So this particular
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product has a chemically defined ingredient, which is called murine
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and murine is a natural inhibitor of xanthine oxidase
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it also stimulates the elimination of uric acid
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through the kidneys. So it has double beneficial affect.
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So murine is found both in roots and in fruits
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of Chinese mulberry and we carry in stock highly
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concentrated fruit extract.
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The next product is Alpha Lipoic Acid.
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Alpha Lipoic Acid has a unique property. So
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Alpha Lipoic Acid stimulates the degredation
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of uric acid and can be combined with White
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Chinese Mulberry Extract as a very powerful
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combination.
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So in order to speed up the elimination of uric acid,
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through gastrointestinal tract, we are utilizing
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yucca root extract, which is known as Yucca Schidigera. And this product works as a soap
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so it kind of washes out uric acid from the gastrointestinal tract.
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In addition we have a brand product called liver detoxifier
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which eliminates uric acid through liver via increased
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elimination with bile and then through the gastrointestinal tract.
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Finally, two oils, Black Currant Seed Oil and Krill Oil
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can significantly reduce production of uric acid in
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the liver and also benefit patients who are trying to lower uric acid.
Dr. Alexander Shikhman describes the benefits and differences between Mannan oligosaccharides and Ga
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So as most of you know intestinal candidiasis
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or a yeast infection in the gut represents a
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very sizeable problem in patients with various
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autoimmune diseases. And we were trying to find
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the best solution and so far we think that
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Candidacillin is one of the best remedies
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available on the market of nutraceuticals
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or food supplements. So where do we stand
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with candida? Well, candida is a part of
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normal gut, or intestinal microflora. Under
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appropriate conditions, candida starts to overgrow
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and occupies much more space in the gut
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compared to what it should be
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and as a consequence, people with intestinal candidiasis
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develop different problems varying from bloating
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fatigue, brain fog, headaches, as well as various
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inflammatory conditions. So why does yeast
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become so aggressive? There are two reasons.
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Reason number one, it occupies more space in the gut
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and is much more metabolized. Reason number two,
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that it becomes more pathogenic.
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So what does that mean? Yeast exists in two forms
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round forms and hyphae. Round forms are low pathogenic
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and don't represent any harm for the human body.
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The budding forms, or hyphae, are much more
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pathogenic, they are invasive forms and they can
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produce various toxins affecting our body and
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overstimulating the immune system.
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So when we target candida, or yeast, we need to
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keep three things in mind. And target three different
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areas. Number one, we need to bring the yeast
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count under control. Number two, we need to
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prevent the hyphae formation and finally, we need
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to prevent biofilm formation.
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I didn't talk much about biofilm
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but yeast forms biofilm and biofilm prevents
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various antibiotics from their antifungal activities.
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Candidacillin, which we designed recently,
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represents a combination of four ingredients.
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Number one is calcium salt of undecylenic acid
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which is an FDA approved remedy to treat candida
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this is an extract from castor oil and it has
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fungicidal activities so what it does, it kills
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the yeast cells. Number two, we have two ingredients
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from coconuts, or coconut oil more specifically,
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one is Monolaurin and second is Caprylic acid
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both ingredients reduce the candida count
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or yeast count in the gut and they kill the yeast as well.
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And finally we decided to add EDTA.
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EDTA is a chelating agent which binds calcium
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and various heavy metals and destroys the biofilms.
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So by combining these four ingredients
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together, we created a very efficient, natural
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remedy to handle candida.
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So what about the dosage of Candidacillin?
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We recommend a dose of two capsules of
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candidacillin before meals twice a day.
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So you can take it before breakfast and before lunch
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or before lunch and before dinner. Ideally
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you need to drink plenty of fluid and take it
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around 20-30 minutes before meals.