Vitamin D3, also known as cholecalciferol, is an active form of vitamin D. Vitamin D is a fat-soluble vitamin which possesses hormone-like activity and regulates calcium and phosphate metabolism. In addition, vitamin D also affects neuromuscular function, inflammation, and influences the action of many genes that regulate cell proliferation and differentiation and programmed cell death.
In adults, the production of vitamin D by skin cells upon sunlight exposure is minimal. Therefore, most of the required vitamin D in adults comes with food.
Vitamin D deficiency in adults can cause osteopenia/osteoporosis, joint pain and abnormal deposition of calcium salts in the joints (pseudogout).
Potential side effects:
- Joint pain
- Muscle pain
- Abdominal pain
Potential drug interactions:
- Aluminum based antacids
- Calcipotriene (Dovonex)
- Calcium channel blockers
- Thiazide diuretics (water pills)
- Cimetidine (Tagamet)
- Low molecular weight heparins
- Strontium Citrate
- High levels of calcium in the blood
- Hardening of the arteries (atherosclerosis)
- Over-active parathyroid gland (hyperparathyroidism)
Contents: 180 softgels
The recommended dose of vitamin D3 varies between 1000 to 10000 units a day and ideally should be adjusted to the blood level of vitamin D.
Bjelakovic G, Gluud LL, Nikolova D, Whitfield K, Wetterslev J, Simonetti RG, Bjelakovic M, Gluud C. Vitamin D supplementation for prevention of mortality in adults. Cochrane Database Syst Rev. 2011 Jul 6;(7):CD007470.
Christakos S, DeLuca HF. Minireview: Vitamin D: is there a role in extraskeletal health? Endocrinology. 2011 Aug;152(8):2930-6.
Henry HL. Regulation of vitamin D metabolism. Best Pract Res Clin Endocrinol Metab. 2011 Aug;25(4):531-41.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
All information contained on this website is intended for informational and educational purposes only, and is not intended nor suited to be a replacement or substitute for professional medical treatment or for professional medical advice relative to a specific medical question or condition.