Magnesium Malate

gluten free magnesium malate

Magnesium is a key macroelement which is involved in more than 300 essential metabolic reactions in the human body including generation of energy, protein, nucleic acid and lipid synthesis, cell signaling, maintenance of bone health and facilitation of muscle contractions among others. The clinical signs of magnesium deficiency manifest in the form of neurological and muscular symptoms (tremor, muscle spasms, tetany), loss of appetite, nausea, vomiting, and personality changes.


There are different preparations of magnesium available as food supplements. The preferred product is magnesium malate. This is based on the fact that the malate portion of the molecule facilitates the production of energy in the body during both aerobic and anaerobic conditions and reduces muscle fatigue.


Potential side effects:

  • Diarrhea
  • Hypotension
  • Dizziness
  • Light-headedness
  • Confusion
  • Muscle weakness

Potential drug interactions:

  • Digoxin
  • Hydroxycloroquine (Plaquenil)
  • Bisphosphonates
  • Nitrofurantoin
  • Chlorpromazine
  • Penicillamine
  • Coumadin
  • Tetracycline antibiotics
  • Quinolone antibiotics

Relative contraindications:

  • Pregnancy
  • Lactation
  • Chronic diarrhea
  • Muscle weakness
  • Chronic anticoagulation therapy
  • End-stage renal disease


Contents: 180 tablets


Dosage Information:

The recommended dose of magnesium varies from 150 to 600 mg of elemental magnesium a day. In general, most people start on 150 mg of magnesium with subsequent dose escalation every 3 to 4 days until they notice mild laxative effect of the remedy. Those exceeding the recommended doses must do so under the supervision of their physician due to the increased risk of potential side effects.


To view supplement facts click here


Selected references:

Guerrera MP, Volpe SL, Mao JJ. Therapeutic uses of magnesium. Am Fam Physician. 2009 Jul 15;80(2):157-62.


Rude RK, Singer FR, Gruber HE. Skeletal and hormonal effects of magnesium deficiency. J Am Coll Nutr. 2009 Apr;28(2):131-41.


Russell IJ, Michalek JE, Flechas JD, Abraham GE. Treatment of fibromyalgia syndrome with Super Malic: a randomized, double blind, placebo controlled, crossover pilot study. J Rheumatol. 1995 May;22(5):953-8.


These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

All information contained on this website is intended for informational and educational purposes only, and is not intended nor suited to be a replacement or substitute for professional medical treatment or for professional medical advice relative to a specific medical question or condition.


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