Cat's Claw

gluten free cat's claw

Cat's claw, also known as Uncaria tomentosa, is a woody vine native to the Amazon rainforest and other places in South and Central America. The bark and root have been used by native South Americans for centuries to treat health problems including arthritis, stomach ulcers, inflammation, dysentery and fevers. It was also used as a form of birth control.


Active ingredients, extracted from the cat’s claw bark, include oxindole alkaloids (isopteropodine, pteropodine, mitraphylline, isomitraphylline, uncarine F, speciophylline, 3-isoajmalicine, 19-epi-3-isoajmalicine, uncarine B), polyhydroxylated triterpenes and plant sterols (beta sitosterol, stigmasterol, campesterol) among others.


Biological studies showed that cat's claw stimulates the immune system (macrophages and natural killer, NK, cells), relaxes smooth muscles in the intestines, dilates blood vessels and lowers blood pressure, and acts as a diuretic. It also possesses antioxidant properties. Some studies suggest that cat' s claw may kill tumor and cancer cells.


Potential side effects:

  • Diarrhea
  • Dizziness
  • Sedative effects
  • Hypotension
  • Hypoglycemia (low blood sugar)

Potential drug interactions:

  • Coumadin
  • Mediations for diabetes
  • Immunosuppressants
  • Medications for hypertension

Relative contraindications:

  • Pregnancy
  • Lactation
  • Autoimmune diseases including lupus
  • Parkinson’s disease
  • Strongly positive ANA antibodies
  • Chronic immunosuppressive therapy
  • Organ transplantation
  • Chronic anticoagulation therapy


Contents: 120 VCaps


Dosage information:

The recommended dose of cat’s claw is 2 tablets 2 times a day with meals. Those exceeding the recommended doses must do so under the supervision of their physician due to the increased risk of potential side effects.


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Selected references:

Ccahuana-Vasquez RA, Santos SS, Koga-Ito CY, Jorge AO. Antimicrobial activity of Uncaria tomentosa against oral human pathogens. Braz Oral Res. 2007 Jan-Mar;21(1):46-50.


Domingues A, Sartori A, Valente LM, Golim MA, Siani AC, Viero RM. Uncaria tomentosa aqueous-ethanol extract triggers an immunomodulation toward a Th2 cytokine profile. Phytother Res. 2011 Aug;25(8):1229-35. doi: 10.1002/ptr.3549.


Erowele GI, Kalejaiye AO. Pharmacology and therapeutic uses of cat's claw. Am J Health Syst Pharm. 2009 Jun 1;66(11):992-5.


Heitzman ME, Neto CC, Winiarz E, Vaisberg AJ, Hammond GB. Ethnobotany, phytochemistry and pharmacology of Uncaria (Rubiaceae). Phytochemistry. 2005 Jan;66(1):5-29.





These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

All information contained on this website is intended for informational and educational purposes only, and is not intended nor suited to be a replacement or substitute for professional medical treatment or for professional medical advice relative to a specific medical question or condition.

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