Methylcobalamin (B12)

gluten free vitamin b12

Methylcobalamin is an active form of vitamin B12. Consumption of high doses of methylcobalamin has been advocated to protect the cognitive function of those suffering chronic fatigue syndrome, stroke, depression, Alzheimer’s disease, and other neurological diseases. The benefits of methylcobalamin are based on its ability to remove brain-damaging levels of the neurotransmitter glutamate.


Potential side effects:

  • Insomnia

Potential drug interactions:

  • Have not been reported

Relative contraindications:

  • Pregnancy
  • Lactation


Contents: 60 lozenges


Dosage information:

The recommended dose of methylcobalamin varies from 1000 to 10000 mcg sublingually once a day. Those exceeding the recommended doses must do so under the supervision of their physician due to the increased risk of potential side effects.


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Selected references:

McCaddon A, Hudson PR. L-methylfolate, methylcobalamin, and N-acetylcysteine in the treatment of Alzheimer’s disease-related cognitive decline. CNS Spectr. 2010 Jan;15(1 Suppl 1):2-5.


Metz J. Cobalamin deficiency and the pathogenesis of nervous system disease. Annu Rev Nutr. 1992;12:59-79.


Banerjee R, Ragsdale SW. The many faces of vitamin B12: catalysis by cobalamin-dependent enzymes. Annu Rev Biochem. 2003;72:209-47.


These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

All information contained on this website is intended for informational and educational purposes only, and is not intended nor suited to be a replacement or substitute for professional medical treatment or for professional medical advice relative to a specific medical question or condition.


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