Leaky gut syndrome is a functional disorder of the gut comprising of abnormal intestinal permeability. The therapy of leaky gut is most efficient and sustainable with the use of butyrate salts and L-glutamine.
Butyrate is a short chain fatty acid derived from the microbial fermentation of dietary fibers in the colon. Butyrate salts, including calcium and magnesium butyrate, are the regulators of intestinal integrity and gene expression (both in the intestine and in various internal organs). At the intestinal level, butyrate regulates fluid transport, controls intestinal permeability, modulates inflammatory and immune responses, suppresses yeast (candida) overgrowth and optimizes intestinal motility. At the whole body level, butyrate regulates glucose and lipid metabolism, prevents certain types of cancers, regulates stem cell and tissue regeneration, reduces ammonia concentration and improves memory and brain function.
L-glutamine is an amino acid and serves as a structural component of various proteins. It plays a vital role in the maintenance of intestinal integrity and permeability, regulates the acid balance in the kidneys and is involved in ammonia synthesis and transportation.
L-glutamine and butyrate salts should not be taken if you are currently taking Coumadin, Allopurinol, anti-seizure medications or Tetracycline. Or if you have acute gout, hypoglycemia, chronic and acute renal insufficiency, chronic anticoagulation therapy; or are pregnant.